When administering phenytoin intravenously, what is the maximum safe rate for the nurse to follow?

The maximum safe rate for administering phenytoin intravenously is established at 50 mg per minute. This rate is important to prevent complications associated with rapid infusion, such as hypotension, cardiac arrhythmias, and phlebitis. Administering phenytoin at this rate allows for effective therapeutic levels while minimizing the risk of adverse effects.

Additionally, phenytoin is contraindicated for rapid infusion due to its propylene glycol content, which can lead to significant cardiovascular issues when infused too quickly. Therefore, adherence to the 50 mg/min guideline ensures patient safety and therapeutic efficacy when treating conditions like seizures.