What is the relationship between seizure activity and ICP levels?

Seizures can significantly impact intracranial pressure (ICP) levels due to the increased metabolic demand they create within the brain. During a seizure, there is a surge in neuronal activity, which requires more oxygen and glucose, leading to heightened cerebral blood flow. This increased blood flow results in an elevation of intracranial volume as more blood is accommodated within the cranial cavity. Since the skull is a rigid structure, any increase in volume from swelling, blood, or other factors leads to elevated ICP. Thus, the relationship demonstrates that seizures can lead to increased ICP levels through the mechanisms of metabolic demand and cerebral blood flow changes.